Interesting Facts about CBD (Cannabidiol)

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CBD has been recognized for its benefits on human and animal health Non-psych toxic: Because it’s made from hemp, CBD does not result in feelings of euphoria, as opposed to marijuana-derived CBD. Hemp-derived CBD has a remarkable safety profile.

You can find all of our high-quality CBD Oils in Pittsburgh, they are made from agricultural hemp and is capable of affecting nearly every biological process. Our CBD oil is made from outdoor grown, chemical-free agricultural hemp. No only does hemp sequester CO2, it is environmentally helpful and is a model of textbook sustainability.

THE ENDOCANNABINOID SYSTEM (ECS)

Sure, saying” endocannabinoid” sounds like a tongue twister, but more importantly, we should all educate ourselves on this newly discovered central regulatory system. Why? Because researchers over the last 30 years have discovered that the ECS is a system that is designed to balance you.

A New Scientific Discovery

So what is the Endocannabinoid System (ECS)?

The ECS is made of cannabinoid receptors, endogenous (self-made) cannabis-like compounds, and enzymes that create and inactivate them. The ECS is one of the most important physiologic systems involved in establishing and maintaining human health. Over 100 phytocannabinoids, like CBD, have been found to exist. They are plant derivatives that “talk” to just about every major organ system in the body via the ECS, helping restore normal balance and physiologic homeostasis.

Endocannabinoids and their receptors are found throughout the body. In each tissue, cannabinoids perform different tasks, but the goal is always the same: homeostasis, maintaining a stable internal environment despite fluctuations in the external environment.

So, why is CBD Important for the ECS?

Because CBD modulates endocannabinoid tone and may help keep healthy people healthy.

What are Cannabinoid Receptors?

UNDERSTANDING THE MECHANISMS OF ACTION-CANNABINOID RECEPTORS ARE AN IMPORTANT CLASS OF CELL MEMBRANE RECEPTORS.

Receptors are akin to” locks,” and the ligand compounds that bind to them are akin to” keys” in a lock & key system. They have about seven sections that pass through the outer cell membrane. Cannabinoid receptors are also coupled to G-proteins, where a lot of the signaling” magic” happens when a molecule or compound binds to the outer portion of these receptors. The three main ligands that bind to cannabinoid receptors are all lipophilic (fatty or” fat-loving” compounds), and include endocannabinoids (synthesized within the body), phytocannabinoids (plant-derived, such as from cannabis), and synthetic cannabinoids.

The cannabinoid receptors are further divided into two main subtypes, known as CB1 and CB2. Although they have some similarity, they are mostly differentiated by what tissue or organ system they are associated within the body.

CB1 receptors: Found mostly in the brain, with some presence in lung, kidney, liver, fat, heart, muscle, and bone. CB1 receptors are mostly associated with the psychoactive and euphoric aspects of THC.

CB2 receptors: Mostly found within the immune system and blood cells, and secondarily in lesser density within the nervous system, liver, gut, muscle, and bone.